UT Health Austin Pediatric Neurosciences at Dell Children's

A. Negri bodies

Negri bodies are the pathologic hallmark of rabies encephalitis. Psammoma bodies are classically associated with meningiomas but also occur with thyroid carcinoma, mesothelioma, and other tumors. Some of these tumors have a good prognosis, and even the more aggressive tumors are indolent compared to rabies. Lewy bodies are associated with Lewy body dementia, a devastating but chronic condition. Nissl bodies are normal neuronal structures made up of endoplasmic reticulum and ribosomes.

Negri bodies are round eosinophilic cytoplasmic inclusion bodies that are pathognomonic for rabies encephalitis. Adelchi Negri described these inclusions in rabid animals in 1903. Occasional reports document survival after contracting rabies encephalitis, but most of these individuals quickly succumb.

Additional reading:

1. de Souza A, Madhusudana SN. Survival from rabies encephalitis. J Neurol Sci. 2014;339(1-2):8-14.

2. Lacy M, Phasuk N, Scholand SJ. Human rabies treatment—from palliation to promise. Viruses. 2024;16(1):160.

3. Warrell MJ. Emerging aspects of rabies infection: with a special emphasis on children. Curr Opin Infect Dis. 2008;21(3):251-257.

4. Henry R, Murphy FA. Etymologia: Negri bodies. Emerg Infect Dis. 2017;23(9):1461.

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Issue 1: February 12, 2026

• A Conversation With Elias Rizk: Chief of Pediatric Neurosurgery
• Featured Articles
• A Second Opinion
• Pediatric Neurosciences Welcomes New Colleagues
• Elected & Selected
• In the News
• Cerebral Palsy Clinic Hosts Second Annual Symposium
• Maher Presents Timothy M. George, MD, Memorial Lecture
• Program Co-Sponsors Fourth Annual Neurofibromatosis Family Day
• Fun Facts From Our Super (Neuro) Bowl
• Upcoming Events

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Issue 1: February 4, 2025

• Rizk Appointed Chief of Pediatric Neurosurgery and Co-Chief of Pediatric Neurosciences
• Featured Article: Preinjury Factors Affect the Course of Concussion in Adolescents
• Pediatric Neurosciences Welcomes New Colleagues
• Elected & Selected
• In the News
• Cerebral Palsy Clinic Co-Hosts First Annual Symposium
• Durham Presents Timothy M. George, MD, Memorial Lecture
• Program Co-Sponsors Third Annual Neurofibromatosis Family Day
• Upcoming Events

Issue 2: July 15, 2025

• Featured Articles
• A Second Opinion
• Dell Children’s Medical Center Adds Portable MRI
• Elected & Selected
• Moodley Retires After Four Decades of Service in Pediatric Neurology
• Program Co-Sponsors Second IMPRES Pediatric Epilepsy Surgery Conference
• Program Hosts Sixth Annual Practical Pediatric Neuroscience Symposium

Issue 3: November 18, 2025

• Kumar Awarded Research Grants to Study Pediatric Brain Tumors
• Featured Articles
• A Second Opinion
• Pediatric Neurosciences Welcomes New Colleagues
• Program Ranked 25 by U.S. News
• Elected & Selected
• In the News
• Biobank Collection Advances Pediatric Neurological Research
• Residency Program Ranks 24 in Nation
• Fun Facts from Our Super (Neuro) Bowl
• Save the Date: IMPRES Pediatric Epilepsy Surgery Conference

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Issue 1: February 13, 2024

• Clarke Receives Penry Award From American Epilepsy Society
• A Second Opinion
• Featured Article: Vitamin-Dependent Genetic Disorders
• Pediatric Neurosciences Welcomes New Colleagues
• Colleagues in the News
• Elected & Selected
• Pediatric Neurosciences Co-Sponsors Second Annual NF Family Day
• Clarke Advocates at National Epilepsy Congressional Briefing
• Wellons Presents at Second Annual Timothy M. George Memorial Symposium
• Upcoming Events

Issue 2: July 30, 2024

• Edmond Meets With Lawmakers for AAO Mid-Year Forum
• Pediatric Neurosciences Hosts First Annual IMPRES Conference
• A Second Opinion
• Brumback Article Summarizes NINDS Research Workshop
• Pediatric Neurosciences Welcomes New Colleagues
• Elected & Selected
• Firefly Fund Kicks Off Center for Rare Disease
• Dell Children’s Hosts Fifth Annual Practical Pediatric Neuroscience Symposium
• Program Hosts Renowned Neurosurgeon Dominic Thompson as Visiting Professor

Issue 3: November 7, 2024

• Clarke to Receive the Gold Humanism Award from the Child Neurology Society
• A Timely Update on Neurocutaneous Syndromes
• Pediatric Neurosciences Ranked by U.S. News
• Pediatric Neurosciences Welcomes New Colleagues
• Elected & Selected

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Issue 1: February 9, 2023

• Are Thalamic Circuits Related to Autism or Other Conditions?
• Pediatric Neurosciences Program Co-Sponsors First Annual Neurofibromatosis Family Day
• Epilepsy Center Expands to North Austin
• Elected and Selected
• Pediatric Neurosciences Program Welcomes Several New Colleagues
• Colleagues in the News
• 3D Printing to Aid Neurosurgery Planning
• Join Us for the Fourth Annual Practical Pediatric Neuroscience Symposium

Issue 2: July 18, 2023

• How Do Epilepsy Center Characteristics Affect Epilepsy Surgery Utilization?
• Autism Research Program Receives Additional NIH Grant
• Dell Children’s Medical Center Hosts Fourth Annual Pediatric Neuroscience Symposium
  
• Elected and Selected
• Pediatric Neurosciences Welcomes New Colleagues
  
• North Campus Epilepsy Center Celebrates Grand Opening
  
• Children’s Tumor Foundation NF Clinic Network Renews Neurofibromatosis Clinic Affiliate Clinic Status
  
• Register for the International Pediatric Headache Didactic Series

Issue 3: October 3, 2023

• Gettig & Austin Create Concussion Training Module for Texas Coaches
• Tradition! Tradition! Tradition?
• A Second Opinion
• Pediatric Neurosciences Welcomes New Colleagues
• Colleagues in the News
• Elected and Selected
• Pediatric Neurosciences Sponsors Sixth Annual Women in Neuroscience Internship
• Save the Date: IMPRES Conference on Pediatric Epilepsy Surgery

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Issue 1: February 22, 2022

• Dramatic Growth of the Pediatric Neurosciences Program Continues
• Pandemic Adaption of Neuropsychological Presurgical Testing
• Pearls & Potholes
• Laser Interstitial Thermal Therapy Adapted For Infants
• New Pediatric Neurology Textbook Released
• Neurofibromatosis Clinic Joins the Children's Tumor Foundation NF Clinic Network
• Audrey Brumback Named to CNS Leadership, Diversity, Equity, and Inclusion Task Force
• Dave Clarke Honored as Top 10 Physician

Issue 2: June 14, 2022

• Bermans Iskandar, MD, Presents the Inaugural Timothy M. George Memorial Lecture in Pediatric Neurosurgery
• Hardy Discusses Protective Factors in Preventing Pediatric-Onset Multiple Sclerosis
• A Second Opinion
• Repetitive Valproate Infusion Shows Promise in Reducing Refractory Chronic Headache Pain
• Dell Children’s Medical Center Hosts Third Annual Pediatric Neuroscience Symposium
• Women in Neuroscience (WiN) Program Encourages Young Women to Pursue Neuroscience Careers
• Vascular Autonomic Lab Opens
• Pediatric Neurosciences Program Welcomes Several New Colleagues
• Our Colleagues in the News

Issue 3: September 30, 2022

• New Child Neurology Society Journal to Be Based in Austin
• Child Neurology Resident Develops Automated Lesion Analysis Algorithm
• Resident Graduates Highlight the Importance of Early Vitamin Replacement
• A Second Opinion
• Pavitt Launches Headache Lectureship Series
• WiNterns Complete 2022 Summer Intensive
• Pediatric Rehab Program Dedicates Panda Cares Center of Hope
• Pediatric Neurosciences Program Ranked by U.S. News
• Pediatric Neurosciences Program Welcomes New Colleagues
• Our Colleagues in the News

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